patent applications

    Górna M, Nowacka M, Izert M, Kowalska M, Karolak N, Klimecka M, Młynarczyk K. Sposób selekcji i/lub wzbogacania RNA, cząsteczka RNA oraz jej zastosowanie (A method of RNA selection and/or enrichment, a RNA molecule and use thereof). P.430151 (05.06.2019), PCT/IB2020/055263 (04.06.2020) WO/2020/245755, US17616459 (03.12.2021)

    Górna M, Izert M, Klimecka M, Szybowska P, Antosiewicz A, Twardowski P. Konstrukty peptydowe do celowanej degradacji białek (Peptide constructs for targeted protein degradation). P.439032 (24.09.2021)

    PREPRINTS

    Klimecka MM, Antosiewicz A, Izert MA, Szybowska PE, Twardowski PK, Delaunay C, Górna MW. A uniform benchmark for testing ssrA-derived degrons in the Escherichia coli ClpXP pathway. (now published in Molecules)

    Merski M, Górna MW. Thiamin-Diphosphate Enzymes Are an Ancient Family of Repeat Proteins. DOI:

    Blanco N, Stafford K, Lavoie MC, Brandenburg A, Gorna MW, Merski M. Prospective Prediction of Future SARS-CoV-2 Infections Using Empirical Data on a National Level to Gauge Response Effectiveness. arXiv:2007.02712 https://arxiv.org/abs/2007.02712 (now published in Epidemiology & Infection)

    Merski M#, Młynarczyk K#, Ludwiczak J, Skrzeczkowski J, Dunin-Horkawicz S, Górna MW. Self-Analysis of Repeat Proteins Reveals Evolutionarily Conserved Patterns. 16 April 2020, PREPRINT (Version 4), available at Research Square, DOI: 10.21203/rs.2.15797/v4 (now published in BMC Bioinformatics)

    IN PRESS

    Izert MA, Szybowska PE, Górna MW, Merski M. (2021) The Effect of Mutations in the TPR and Ankyrin Families of Alpha Solenoid Repeat Proteins.
    Front. Bioinform. 1:696368. doi: 10.3389/fbinf.2021.696368

    Go!RNA lab publications

    1. Klimecka MM Antosiewicz A# Izert MA# Szybowska PE Twardowski PK Delaunay C Górna MW 2021 A Uniform Benchmark for Testing SsrA-Derived Degrons in the Escherichia coli ClpXP Degradation Pathway. Molecules 26195936
    2. Izert MA Klimecka MM Górna MW 2021 Applications of Bacterial Degrons and Degraders - Toward Targeted Protein Degradation in Bacteria. Front Mol Biosci 8669762
    3. Blanco N Stafford K Lavoie MC Brandenburg A Górna MW Merski M 2021 A Simple Model for the Total Number of SARS-CoV-2 Infections on a National Level. Epidemiol Infect 149e80
    4. Brunner JS Vogel A Lercher A Caldera M Korosec A Pühringer M Hofmann M Hajto A Kieler M Garrido LQ Kerndl M Kuttke M Mesteri I Górna MW Kulik M Dominiak PM Brandon AE Estevez E Egan CL Gruber F Schweiger M Menche J Bergthaler A Weichhart T Klavins K Febbraio MA Sharif O Schabbauer G 2020 The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages. Nat Metab 2121427-1442
    5. Merski M Skrzeczkowski J Roth JK Górna MW 2020 A Geometric Definition of Short to Medium Range Hydrogen-Mediated Interactions in Proteins. Molecules 25225326
    6. Jarnot P Ziemska-Legiecka J Dobson L Merski M Mier P Andrade-Navarro MA Hancock JM Dosztányi Z Paladin L Necci M Piovesan D Tosatto SCE Promponas VJ Grynberg M Gruca A 2020 PlaToLoCo: the first web meta-server for visualization and annotation of low complexity regions in proteins. Nucleic Acids Res gkaa339
    7. Merski M# Młynarczyk K# Ludwiczak J Skrzeczkowski J Dunin-Horkawicz S Górna MW 2020 Self-analysis of repeat proteins reveals evolutionarily conserved patterns. BMC Bioinformatics 211179
    8. Kutner J# Shabalin IG# Matelska D Handing KB Gasiorowska O Sroka P Gorna MW Ginalski K Wozniak K Minor W 2018 Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry 576963-977

    #Equal contribution

    Maria Górna – publication list

    1. Klimecka MM Antosiewicz A# Izert MA# Szybowska PE Twardowski PK Delaunay C Górna MW 2021 A Uniform Benchmark for Testing SsrA-Derived Degrons in the Escherichia coli ClpXP Degradation Pathway. Molecules 26195936
    2. Izert MA Klimecka MM Górna MW 2021 Applications of Bacterial Degrons and Degraders - Toward Targeted Protein Degradation in Bacteria. Front Mol Biosci 8669762
    3. Blanco N Stafford K Lavoie MC Brandenburg A Górna MW Merski M 2021 A Simple Model for the Total Number of SARS-CoV-2 Infections on a National Level. Epidemiol Infect 149e80
    4. Brunner JS Vogel A Lercher A Caldera M Korosec A Pühringer M Hofmann M Hajto A Kieler M Garrido LQ Kerndl M Kuttke M Mesteri I Górna MW Kulik M Dominiak PM Brandon AE Estevez E Egan CL Gruber F Schweiger M Menche J Bergthaler A Weichhart T Klavins K Febbraio MA Sharif O Schabbauer G 2020 The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages. Nat Metab 2121427-1442
    5. Merski M Skrzeczkowski J Roth JK Górna MW 2020 A Geometric Definition of Short to Medium Range Hydrogen-Mediated Interactions in Proteins. Molecules 25225326
    6. Merski M# Młynarczyk K# Ludwiczak J Skrzeczkowski J Dunin-Horkawicz S Górna MW 2020 Self-analysis of repeat proteins reveals evolutionarily conserved patterns. BMC Bioinformatics 211179
    7. Kutner J# Shabalin IG# Matelska D Handing K Gasiorowska O Sroka P Gorna MW Ginalski K Wozniak K Minor W 2018 Structural, biochemical, and evolutionary characterization of glyoxylate/hydroxypyruvate reductases shows their division into two distinct subfamilies. Biochemistry 576963-977
    8. Byrgazov K Kastner R Gorna M Hoermann G Koenig M Lucini CB Ulreich R Benesch M Strenger V Lackner H Schwinger W Sovinz P Haas OA van den Heuvel-Eibrink M Niemeyer CM Hantschel O Valent P Superti-Furga G Urban C Dworzak MN Lion T 2017 NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors. Leukemia 311237-240
    9. Dikoglu E Alfaiz A Gorna M Bertola D Chae JH Cho TJ Derbent M Alanay Y Guran T Kim OH Llerenar JC Jr Yamamoto G Superti-Furga G Reymond A Xenarios I Stevenson B Campos-Xavier B Bonafé L Superti-Furga A Unger S 2015 Mutations in LONP1, a mitochondrial matrix protease, cause CODAS syndrome. Am J Med Genet A 16771501-9
    10. Dölker N# Górna MW# Sutto L Torralba AS Superti-Furga G Gervasio FL 2014 The SH2 domain regulates c-Abl kinase activation by a cyclin-like mechanism and remodulation of the hinge motion. PLoS Comput Biol 1010e1003863
    11. Bonafé L# Liang J# Gorna MW# Zhang Q Ha-Vinh R Campos-Xavier AB Unger S Beckmann JS Le Béchec A Stevenson B Giedion A Liu X Superti-Furga G Wang W Spahr A Superti-Furga A 2014 MMP13 mutations are the cause of recessive metaphyseal dysplasia, Spahr type. Am J Med Genet A 164A51175-9
    12. Vladimer GI Górna MW Superti-Furga G 2014 IFITs: Emerging Roles as Key Anti-Viral Proteins. Front Immunol 594
    13. Unger S# Górna MW# Le Béchec A Do Vale-Pereira S Bedeschi MF Geiberger S Grigelioniene G Horemuzova E Lalatta F Lausch E Magnani C Nampoothiri S Nishimura G Petrella D Rojas-Ringeling F Utsunomiya A Zabel B Pradervand S Harshman K Campos-Xavier B Bonafé L Superti-Furga G Stevenson B Superti-Furga A 2013 FAM111A mutations result in hypoparathyroidism and impaired skeletal development. Am J Hum Genet 926990-5
    14. Abbas YM Pichlmair A# Górna MW# Superti-Furga G Nagar B 2013 Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins. Nature 494743560-4
    15. Bandyra KJ Said N Pfeiffer V Górna MW Vogel J Luisi BF 2012 The seed region of a small RNA drives the controlled destruction of the target mRNA by the endoribonuclease RNase E. Mol Cell 476943-53
    16. Górna MW Carpousis AJ Luisi BF 2012 From conformational chaos to robust regulation: the structure and function of the multi-enzyme RNA degradosome. Q Rev Biophys 452105-45
    17. Pichlmair A Lassnig C Eberle CA Górna MW Baumann CL Burkard TR Bürckstümmer T Stefanovic A Krieger S Bennett KL Rülicke T Weber F Colinge J Müller M Superti-Furga G 2011 IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA. Nat Immunol 127624-30
    18. Goncalves A Bürckstümmer T Dixit E Scheicher R Górna MW Karayel E Sugar C Stukalov A Berg T Kralovics R Planyavsky M Bennett KL Colinge J Superti-Furga G 2011 Functional dissection of the TBK1 molecular network. PLoS One 69e23971
    19. Górna MW Pietras Z Tsai YC Callaghan AJ Hernández H Robinson CV Luisi BF 2010 The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome. RNA 163553-62
    20. Worrall JA# Górna M# Crump NT Phillips LG Tuck AC Price AJ Bavro VN Luisi BF 2008 Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome. J Mol Biol 3824870-83
    21. Worrall JA Górna M Pei XY Spring DR Nicholson RL Luisi BF 2007 Design and chance in the self-assembly of macromolecules. Biochem Soc Trans 35Pt 3502-7

    #Equal contribution

    H-Index

    (Scopus)
    11

    5-Year IF

    (Scopus)
    >140

    Citations

    (excl. autocitations)
    1000+