patent applications

    Górna M, Nowacka M, Izert M, Kowalska M, Karolak N, Klimecka M, Młynarczyk K. Sposób selekcji i/lub wzbogacania RNA, cząsteczka RNA oraz jej zastosowanie (A method of RNA selection and/or enrichment, a RNA molecule and use thereof). P.430151 (05.06.2019), PCT/IB2020/055263 (04.06.2020)

    PREPRINTS

    Merski M, Górna MW. Thiamin-Diphosphate Enzymes Are an Ancient Family of Repeat Proteins. DOI:

    Blanco N, Stafford K, Lavoie MC, Brandenburg A, Gorna MW, Merski M. Prospective Prediction of Future SARS-CoV-2 Infections Using Empirical Data on a National Level to Gauge Response Effectiveness. arXiv:2007.02712 https://arxiv.org/abs/2007.02712 (now published in Epidemiology & Infection)

    Merski M#, Młynarczyk K#, Ludwiczak J, Skrzeczkowski J, Dunin-Horkawicz S, Górna MW. Self-Analysis of Repeat Proteins Reveals Evolutionarily Conserved Patterns. 16 April 2020, PREPRINT (Version 4), available at Research Square, DOI: 10.21203/rs.2.15797/v4 (now published in BMC Bioinformatics)

    IN PRESS

    Izert MA, Klimecka MM, Górna MW. Applications of bacterial degrons and degraders - towards targeted protein degradation in bacteria. Front. Mol. Biosci. (2021) doi: 10.3389/fmolb.2021.669762. Review.

    Go!RNA lab publications

    1. Blanco N Stafford K Lavoie MC Brandenburg A Górna MW Merski M 2021 A Simple Model for the Total Number of SARS-CoV-2 Infections on a National Level. Epidemiol Infect 1-25
    2. Brunner JS Vogel A Lercher A Caldera M Korosec A Pühringer M Hofmann M Hajto A Kieler M Garrido LQ Kerndl M Kuttke M Mesteri I Górna MW Kulik M Dominiak PM Brandon AE Estevez E Egan CL Gruber F Schweiger M Menche J Bergthaler A Weichhart T Klavins K Febbraio MA Sharif O Schabbauer G 2020 The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages. Nat Metab 2121427-1442
    3. Merski M Skrzeczkowski J Roth JK Górna MW 2020 A Geometric Definition of Short to Medium Range Hydrogen-Mediated Interactions in Proteins. Molecules 25225326
    4. Jarnot P Ziemska-Legiecka J Dobson L Merski M Mier P Andrade-Navarro MA Hancock JM Dosztányi Z Paladin L Necci M Piovesan D Tosatto SCE Promponas VJ Grynberg M Gruca A 2020 PlaToLoCo: the first web meta-server for visualization and annotation of low complexity regions in proteins. Nucleic Acids Res gkaa339
    5. Merski M# Młynarczyk K# Ludwiczak J Skrzeczkowski J Dunin-Horkawicz S Górna MW 2020 Self-analysis of repeat proteins reveals evolutionarily conserved patterns. BMC Bioinformatics 211179
    6. Kutner J# Shabalin IG# Matelska D Handing KB Gasiorowska O Sroka P Gorna MW Ginalski K Wozniak K Minor W 2018 Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies. Biochemistry 576963-977

    #Equal contribution

    Maria Górna – publication list

    1. Blanco N Stafford K Lavoie MC Brandenburg A Górna MW Merski M 2021 A Simple Model for the Total Number of SARS-CoV-2 Infections on a National Level. Epidemiol Infect 1-25
    2. Brunner JS Vogel A Lercher A Caldera M Korosec A Pühringer M Hofmann M Hajto A Kieler M Garrido LQ Kerndl M Kuttke M Mesteri I Górna MW Kulik M Dominiak PM Brandon AE Estevez E Egan CL Gruber F Schweiger M Menche J Bergthaler A Weichhart T Klavins K Febbraio MA Sharif O Schabbauer G 2020 The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages. Nat Metab 2121427-1442
    3. Merski M Skrzeczkowski J Roth JK Górna MW 2020 A Geometric Definition of Short to Medium Range Hydrogen-Mediated Interactions in Proteins. Molecules 25225326
    4. Merski M# Młynarczyk K# Ludwiczak J Skrzeczkowski J Dunin-Horkawicz S Górna MW 2020 Self-analysis of repeat proteins reveals evolutionarily conserved patterns. BMC Bioinformatics 211179
    5. Kutner J# Shabalin IG# Matelska D Handing K Gasiorowska O Sroka P Gorna MW Ginalski K Wozniak K Minor W 2018 Structural, biochemical, and evolutionary characterization of glyoxylate/hydroxypyruvate reductases shows their division into two distinct subfamilies. Biochemistry 576963-977
    6. Byrgazov K Kastner R Gorna M Hoermann G Koenig M Lucini CB Ulreich R Benesch M Strenger V Lackner H Schwinger W Sovinz P Haas OA van den Heuvel-Eibrink M Niemeyer CM Hantschel O Valent P Superti-Furga G Urban C Dworzak MN Lion T 2017 NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors. Leukemia 311237-240
    7. Dikoglu E Alfaiz A Gorna M Bertola D Chae JH Cho TJ Derbent M Alanay Y Guran T Kim OH Llerenar JC Jr Yamamoto G Superti-Furga G Reymond A Xenarios I Stevenson B Campos-Xavier B Bonafé L Superti-Furga A Unger S 2015 Mutations in LONP1, a mitochondrial matrix protease, cause CODAS syndrome. Am J Med Genet A 16771501-9
    8. Dölker N# Górna MW# Sutto L Torralba AS Superti-Furga G Gervasio FL 2014 The SH2 domain regulates c-Abl kinase activation by a cyclin-like mechanism and remodulation of the hinge motion. PLoS Comput Biol 1010e1003863
    9. Bonafé L# Liang J# Gorna MW# Zhang Q Ha-Vinh R Campos-Xavier AB Unger S Beckmann JS Le Béchec A Stevenson B Giedion A Liu X Superti-Furga G Wang W Spahr A Superti-Furga A 2014 MMP13 mutations are the cause of recessive metaphyseal dysplasia, Spahr type. Am J Med Genet A 164A51175-9
    10. Vladimer GI Górna MW Superti-Furga G 2014 IFITs: Emerging Roles as Key Anti-Viral Proteins. Front Immunol 594
    11. Unger S# Górna MW# Le Béchec A Do Vale-Pereira S Bedeschi MF Geiberger S Grigelioniene G Horemuzova E Lalatta F Lausch E Magnani C Nampoothiri S Nishimura G Petrella D Rojas-Ringeling F Utsunomiya A Zabel B Pradervand S Harshman K Campos-Xavier B Bonafé L Superti-Furga G Stevenson B Superti-Furga A 2013 FAM111A mutations result in hypoparathyroidism and impaired skeletal development. Am J Hum Genet 926990-5
    12. Abbas YM Pichlmair A# Górna MW# Superti-Furga G Nagar B 2013 Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins. Nature 494743560-4
    13. Bandyra KJ Said N Pfeiffer V Górna MW Vogel J Luisi BF 2012 The seed region of a small RNA drives the controlled destruction of the target mRNA by the endoribonuclease RNase E. Mol Cell 476943-53
    14. Górna MW Carpousis AJ Luisi BF 2012 From conformational chaos to robust regulation: the structure and function of the multi-enzyme RNA degradosome. Q Rev Biophys 452105-45
    15. Pichlmair A Lassnig C Eberle CA Górna MW Baumann CL Burkard TR Bürckstümmer T Stefanovic A Krieger S Bennett KL Rülicke T Weber F Colinge J Müller M Superti-Furga G 2011 IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA. Nat Immunol 127624-30
    16. Goncalves A Bürckstümmer T Dixit E Scheicher R Górna MW Karayel E Sugar C Stukalov A Berg T Kralovics R Planyavsky M Bennett KL Colinge J Superti-Furga G 2011 Functional dissection of the TBK1 molecular network. PLoS One 69e23971
    17. Górna MW Pietras Z Tsai YC Callaghan AJ Hernández H Robinson CV Luisi BF 2010 The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome. RNA 163553-62
    18. Worrall JA# Górna M# Crump NT Phillips LG Tuck AC Price AJ Bavro VN Luisi BF 2008 Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome. J Mol Biol 3824870-83
    19. Worrall JA Górna M Pei XY Spring DR Nicholson RL Luisi BF 2007 Design and chance in the self-assembly of macromolecules. Biochem Soc Trans 35Pt 3502-7

    #Equal contribution

    H-Index

    (Scopus)
    11

    5-Year IF

    (Scopus)
    >140

    Citations

    (excl. autocitations)
    900+