Verifying hydrogen bonds in proteins

A Geometric Definition of Short to Medium Range Hydrogen Mediated Interactions in Proteins.

Merski M, Skrzeczkowski J, Roth JK, Górna MW.

Molecules 25(22), 5326 (2020). https://doi.org/10.3390/molecules25225326

We assessed hydrogen-mediated interactions in protein crystal structures based on the geometry of heavy atoms. This allowed us to describe a conserved set of interactions for various donor and acceptor atom types that may be useful in protein design.

This work was supported by the MINIATURA grant (National Science Centre, Poland, #2017/01/X/NZ1/00567 to M.M.) and by the EMBO Installation Grant (EMBO Bridging Fund, to M.W.G.)