Jan Kutner

Jan Kutner, Ph.D.

Postdoctoral Fellow, Lab Manager

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Research positions and degrees

Since 2015 Postdoctoral fellow with Dr. Maria Gorna, SONATA Project, MSHE „Structure-function studies of RNA-binding proteins with FAST motifs and a RAP domain”, Structural Biology Group, Biomacromolecular Research Laboratory, Biological and Chemical Research Centre, Department of Chemistry, University of Warsaw.

Since 2015 Assistant Professor, Department of Chemistry, Laboratory for Structural and Biochemical Research (BCRC UW) headed by Prof. Krzysztof Wozniak (Crystallochemistry Laboratory, Department of Chemistry, UW).

2015 Visiting Instructor, SKILLS Internship from Foundation for Polish Science in Professor Wladek Minor Laboratory in Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, USA.

2011 – 2015 Postdoctoral fellow with Dr. Krzysztof Ginalski, TEAM Project, Foundation for Polish Science „Application of systems biology to study important processes in Saccharomyces cerevisiae ”, Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies (CeNT), University of Warsaw.

2007 – 2011 Postdoctoral fellow with Dr. Krzysztof Ginalski in Prof. Andrzej Dziembowski group, Laboratory of RNA Biology and Functional Genomics, Institute of Biochemistry and Biophysics (IBB) Polish Academy of Sciences, Warsaw, Poland.

2007 PhD in Biochemistry, supervisor - Prof. Magdalena Boguta, Department of Genetics, Institute of Biochemistry and Biophysics (IBB), Polish Academy of Sciences, Warsaw. „Genetic interactions of MRF1 encoding yeast mitochondrial release factor”.

2002 MSc in Biotechnology, supervisors - Prof. Jan Plenkiewicz, Faculty of Chemistry, Technical University of Warsaw and Dr. Aleksandra Wysłouch-Cieszyńska, Department of Biophysics, Institute of Biochemistry and Biophysics (IBB), Polish Academy of Sciences, Warsaw, Poland „Semisynthesis of selectively phosphorylated inhibitor 4E-BP1 of initiation of translation”.

Research Projects

Since 2016 SYNERGY Swiss National Science Foundation “Design, Synthesis and Characterization of Lipidic Nanomaterials for Biomedical and Biosensing Applications” – University of Zurich and ETH, cooperation with Professor Renata Bilewicz ; collaborator.

Since 2015 MSHE Grant „Structure-function studies of RNA-binding proteins with FAST motifs and a RAP domain”, Structural Biology Group, Biomacromolecular Research Laboratory, Biological and Chemical Research Centre, Department of Chemistry, University of Warsaw, researcher.

Since 2015 Research project “Multifaceted studies of glyoxylate/hydroxypyruvate reductases”, cooperation between Professor Wladek Minor Laboratory in Department of Molecular Physiology and Biological Physics, University of Virginia, USA, and Prof. Krzysztof Wozniak Crystallochemistry Laboratory, Department of Chemistry, University of Warsaw, and Dr. Krzysztof Ginalski Laboratory of Bioinformatics and Systems Biology, (CeNT, UW); project leader.

2013 Research and development grant for young scientists (DSM) „Novel RNA methyltransferases in yeast Saccharomyces cerevisiae”, 212633/E-343/M/2013, Centre of New Technologies (CeNT), University of Warsaw, grant leader.

2009 – 2010 Polish Agency for Enterprise Development (PARP) Grant „Genomes database of biological organisms” POIG.01.04.00-14-036/09-00, researcher.

2008 – 2012 MSHE Grant „Application of systems biology approach to study methylation in Saccharomyces cerevisiae”, N N301 246436, Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies (CeNT), University of Warsaw, grant leader.

2008 – 2011 MSHE Grant „Identification and characterization of novel protein domains involved in nucleic acid metabolism in eukaryotes”, N N301 159435, Laboratory of Bioinformatics and Systems Biology, Centre of New Technologies (CeNT), University of Warsaw, researcher

2004 – 2006 Researcher in MSHE Grant during PhD study.

Awards and Fellowships

2015 SKILLS Internship Scholarship from Foundation for Polish Science (FNP).

2013 Polish Biochemical Society Award in the honor of J.K. Parnas, “The best experimental work in biochemistry or molecular biology made entirely in the Polish laboratory”.

2013 Polish Biochemical Society Award in the honor of J.K. Parnas for “The best experimental or theoretical work in chemistry and biochemistry of nucleic acids, performed mainly in the Polish laboratory”.

2010 – 2015 Postdoctoral fellowship, , TEAM Project, Foundation for Polish Science.

2007 – 2012 FOCUS Scholarship, Foundation for Polish Science.

2007 Ministry of Science and Higher Education Award for the best team in the category "Demonstration at the Festival of Science" for Scientific Happening Night Investigator

2004, 2006 Two mini grants, School of Molecular Biology and PhD Studies, Institute of Biochemistry and Biophysics (IBB), Polish Academy of Sciences, Warsaw, Poland.

Research Interest:

  • Expression, optimization and purification for challenging protein
  • Enzyme kinetics
  • Enzyme activity assays (Protein,RNA and Small Molecule)
  • Protocols development and optimization of molecular biology, biochemistry and macromolecular crystallization experiments
  • Protein structure determination and refinement

Teaching & Team Supervision

  • Design and teching of experimental classes in molecular biology for undergraduate students
  • Co-Organizer of exercises during the Festival of Science
  • Supervision of several undergraduate and graduate students from the Technical University of Warsaw, University of Warsaw and at the University of Virginia

Laboratory Management

I have co-designed and completed laboratory equipment and office space for:

During the setup of the latter laboratory, I was responsible for selection of the essential equipment (pipettes, FPLC, crystallographic robotic systems, etc.). My other areas of responsibility were: creating tender documentation, negotiation with companies, equipment delivery and installation, and employee training. Moreover, I conducted meetings with all the scientists involved in this multidisciplinary project. Due to my organizational skills, I have been hired as a Lab Manager in Structural Biology Group, BCRC, UW.

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